1 Aaron Rodgers, Green Bay vs. N.Y. Giants
2 Ben Roethlisberger, Pittsburgh vs. N.Y. Jets …In his past 16 games at Heinz Field, Roethlisberger is averaging 341 passing yards and 2.9 TDs per game while quarterbacks are completing 71.4 percent of passes against the Jets’ defense (worst in the league)
3 Tom Brady, New England at Cleveland …It will no doubt be the marquee story as Tom Brady makes his 2016 debut
4 Andrew Luck, Indianapolis vs. Chicago …Maybe Luck can find easier sledding at home against Chicago — Luck is on pace to collect 60 sacks
5 Derek Carr, Oakland vs. San Diego
6 Philip Rivers, San Diego at Oakland …Oakland allows an NFL-worst 325.5 passing yards per game
7 Eli Manning, N.Y. Giants at Green Bay …Manning has thrown for just 1 TD each of the past three games, but this should be a game where he gets back to bigger numbers
8 Carson Wentz, Philadelphia at Detroit …Wentz has been incredible to start his NFL career, off a BYE to prepare and Detroit allows the 2nd-most fantasy points to opposing quarterbacks
9 Matthew Stafford, Detroit vs. Philadelphia …Philadelphia allows the fewest per game fantasy points to opposing quarterbacks this season, and haven’t allowed a passing touchdown this year
10 Matt Ryan, Atlanta at Denver …Ryan is on fire, although Denver has allowed under 210 yards passing in every game thus far this year
11 Joe Flacco, Baltimore vs. Washington
12 Derek Anderson, Carolina vs. Tampa Bay …UPDATE: Anderson will be the starter with Cam Newton (concussion) ruled OUT
13 Kirk Cousins, Washington at Baltimore
14 Andy Dalton, Cincinnati at Dallas …Somewhat quietly, Dalton is averaging 309 yards passing per game
15 Brian Hoyer, Chicago at Indianapolis …Hoyer has tossed up back-to-back 300-yard games with 2 TDs in each and gets a soft draw this week at Indianapolis to perhaps extend that streak
16 Jameis Winston, Tampa Bay at Carolina
17 Ryan Tannehill, Miami vs. Tennessee
18 Dak Prescott, Dallas vs. Cincinnati
19 Tyrod Taylor, Buffalo at Los Angeles
20 Paxton Lynch, Denver vs. Atlanta …UPDATE: Lynch will get the start with Trevor Siemian (sprained shoulder) OUT
21 Ryan Fitzpatrick, N.Y. Jets at Pittsburgh
22 Sam Bradford, Minnesota vs. Houston
23 Marcus Mariota, Tennessee at Miami
24 Brock Osweiler, Houston at Minnesota …Osweiler has now thrown an interception in every game as a Texan and gets a fierce Vikings’ defense this week
25 Case Keenum, Los Angeles vs. Buffalo
26 Blaine Gabbert, San Francisco vs. Arizona
27 Cody Kessler, Cleveland vs. New England
28 Drew Stanton, Arizona at San Francisco …Stanton will get the start with Carson Palmer (concussion) out


Running Back
1 DeMarco Murray, Tennessee at Miami …Murray is a complete workhorse back, accounting for 36.4 percent of the Titans’ yardage this year, the most of any player
2 LeVeon Bell, Pittsburgh vs. N.Y. Jets …It won’t likely matter much but the Jets allow just 70.2 rushing yards per week, 2nd-best in the NFL
3 Ezekiel Elliott, Dallas vs. Cincinnati …With 412 rushing yards, Elliott is quickly your 2016 NFL rushing leader
4 David Johnson, Arizona at San Francisco …San Francisco allows 140.5 yards rushing per week, most in the league
5 Melvin Gordon, San Diego at Oakland
6 LeSean McCoy, Buffalo at Los Angeles
7 C.J. Anderson, Denver vs. Atlanta
8 Jordan Howard, Chicago at Indianapolis
9 Carlos Hyde, San Francisco vs. Arizona
10 Todd Gurley, Los Angeles vs. Buffalo …Well, one major positive from Week 4 is Gurley saw a career-high five receptions; UPDATE: reports from Rams’ practices all week continue to emphasize how many reps Gurley is getting catching the ball
11 Eddie Lacy, Green Bay vs. N.Y. Giants
12 Devonta Freeman, Atlanta at Denver
13 Frank Gore, Indianapolis vs. Chicago
14 Jerick McKinnon, Minnesota vs. Houston
15 DeAndre Washington, Oakland vs. San Diego …San Diego allows the 2nd-most fantasy points to opposing running backs; UPDATE: Latavius Murray has been ruled OUT, leaving Washington as the starter and a great Week 5 sleeper
16 Lamar Miller, Houston at Minnesota …Miller is getting the work, but he still hasn’t scored as a Texan
17 LeGarrette Blount, New England at Cleveland
18 Theo Riddick, Detroit vs. Philadelphia
19 Isaiah Crowell, Cleveland vs. New England …You have to give Isaiah Crowell some credit, averaging 110 yards per game with a 6.4 yards per carry average on a team that is now 0-4
20 Terrance West, Baltimore vs. Washington …At some point rookie Kenneth Dixon could/should have this job, but West got the start last week and delivered a strong performance with 113 rushing yards and a score
21 Jeremy Hill, Cincinnati at Dallas …Hill can always get a rushing touchdown (he has three on the season), but he isn’t much of a factor in the passing game and is averaging just 55 yards rushing per game this season
22 Jacquizz Rodgers, Tampa Bay at Carolina …UPDATE: Rodgers will likely get the start with Charles Sims (knee) listed as Doubtful
23 Matt Forte, N.Y. Jets at Pittsburgh …Assuming the Jets get behind again (which seems likely at Pittsburgh), Forte looks slotted for a disappointing game
24 Giovani Bernard, Cincinnati at Dallas
25 Darren Sproles, Philadelphia at Detroit
26 Matt Jones, Washington at Baltimore
27 Duke Johnson Jr., Cleveland vs. New England
28 Fozzy Whittaker, Carolina vs. Tampa Bay
29 Ryan Mathews, Philadelphia at Detroit
30 Cameron Artis-Payne, Carolina vs. Tampa Bay
31 Wendell Smallwood, Philadelphia at Detroit
32 Bilal Powell, N.Y. Jets at Pittsburgh
33 Devontae Booker, Denver vs. Atlanta
34 Chris Thompson, Washington at Baltimore
“35 Tevin Coleman, Atlanta at Denver …We won’t know until the game most likely, but Coleman could be sat this week with the game in the high elevation at Denver due to having a sickle cell
36 James White, New England at Cleveland
37 Bobby Rainey, N.Y. Giants at Green Bay
38 Derrick Henry, Tennessee at Miami
39 Jalen Richard, Oakland vs. San Diego …UPDATE: Richard moves up in the final Week 5 rankings with Latavius Murray ruled OUT
40 Matt Asiata, Minnesota vs. Houston
41 Kenneth Dixon, Baltimore vs. Washington …Expect Dixon to be eased in, but he is expected to make his NFL debut this week
42 Jay Ajayi, Miami vs. Tennessee
43 Josh Ferguson, Indianapolis vs. Chicago
44 DeAngelo Williams, Pittsburgh vs. N.Y. Jets
45 Mike Gillislee, Buffalo at Los Angeles
46 Orleans Darkwa, N.Y. Giants at Green Bay
47 Dexter McCluster, San Diego at Oakland
48 James Starks, Green Bay vs. N.Y. Giants
49 Kenyan Drake, Miami vs. Tennessee
50 Andre Ellington, Arizona at San Francisco …Ellington could be back on fantasy radar after Chris Johnson has been placed on Injured Reserve
51 Alfred Morris, Dallas vs. Cincinnati
52 Zach Zenner, Detroit vs. Philadelphia …Zenner will be forced into action with Dwayne Washington (ankle) likely to miss some time
53 Rashad Jennings, N.Y. Giants at Green Bay …Jennings (thumb) will need to be monitored, but either way he goes against a Packers’ defense that allow a league-best 42.7 rushing yards per week; UPDATE: Jennings looks likely to sit again
54 Charles Sims, Tampa Bay at Carolina …UPDATE: Sims (knee) is a risky play after missing practice this all week
55 Benny Cunningham, Los Angeles vs. Buffalo
56 Mike Tolbert, Carolina vs. Tampa Bay
57 Kenjon Barner, Philadelphia at Detroit
58 Shaun Draughn, San Francisco vs. Arizona
59 Javorius Allen, Baltimore vs. Washington
60 Paul Perkins, N.Y. Giants at Green Bay


Wide Receivers
1 Antonio Brown, Pittsburgh vs. N.Y. Jets
2 A.J. Green, Cincinnati at Dallas
3 Odell Beckham Jr., N.Y. Giants at Green Bay …ODB has to be due at some point as he still hasn’t collected a touchdown in 2016
4 Jarvis Landry, Miami vs. Tennessee
5 Jordy Nelson, Green Bay vs. N.Y. Giants
6 Mike Evans, Tampa Bay at Carolina …You have to trust the volume (Evans is on pace for exactly 200 targets), and Carolina’s young defensive backs just got roasted by Julio Jones
7 Demaryius Thomas, Denver vs. Atlanta
8 T.Y. Hilton, Indianapolis vs. Chicago
9 Julio Jones, Atlanta at Denver …Jones is elite enough to blast through this ranking, although Denver allows the fewest fantasy points to opposing wide receivers
10 Kelvin Benjamin, Carolina vs. Tampa Bay …Regardless of who starts at quarterback for the Panthers, Benjamin should be effective against a defense that allows the 2nd-most fantasy points to opposing receivers
11 Michael Crabtree, Oakland vs. San Diego
12 Brandon Marshall, N.Y. Jets at Pittsburgh
13 Alshon Jeffery, Chicago at Indianapolis …With Kevin White out, Jeffery should get added targets this week in a very favorable match-up
14 Emmanuel Sanders, Denver vs. Atlanta
15 Sterling Shepard, N.Y. Giants at Green Bay
16 Marvin Jones, Detroit vs. Philadelphia
17 Amari Cooper, Oakland vs. San Diego
18 DeAndre Hopkins, Houston at Minnesota …Hopkins has just 33 targets through four weeks (this time last year he had 60)
19 Terrelle Pryor, Cleveland vs. New England
20 Jordan Matthews, Philadelphia at Detroit
21 Steve Smith Sr., Baltimore vs. Washington
22 Randall Cobb, Green Bay vs. N.Y. Giants
23 Julian Edelman, New England at Cleveland …UPDATE: Edelman (foot) was added to the injury report late in the week but he put in a limited practice Friday
24 Cole Beasley, Dallas vs. Cincinnati
25 Robert Woods, Buffalo at Los Angeles …With Sammy Watkins out, Woods has collected 13 receptions the last weeks acting as the Bills’ number one wideout
26 Larry Fitzgerald, Arizona at San Francisco …It’s a week to downgrade Fitzgerald and the other Cardinals’ wide receivers with Carson Palmer (concussion) unlikely to play
27 DeSean Jackson, Washington at Baltimore
28 Golden Tate, Detroit vs. Philadelphia
29 Will Fuller, Houston at Minnesota
30 Sammie Coates, Pittsburgh vs. N.Y. Jets …Coates has collected five 40+ yard passes, the most in the NFL this year
31 Davante Adams, Green Bay vs. N.Y. Giants
32 Quincy Enunwa, N.Y. Jets at Pittsburgh
33 Mike Wallace, Baltimore vs. Washington
34 Anquan Boldin, Detroit vs. Philadelphia
35 Chris Hogan, New England at Cleveland …Hogan hasn’t done much, but the switch to Tom Brady could make him an instant Week 5 sleeper (Hogan caught five receptions with a touchdown from Brady in the Week 3 pre-season tune-up game)
36 Travis Benjamin, San Diego at Oakland
37 Tyrell Williams, San Diego at Oakland
38 Victor Cruz, N.Y. Giants at Green Bay
39 DeVante Parker, Miami vs. Tennessee
40 Kenny Stills, Miami vs. Tennessee
41 Phillip Dorsett, Indianapolis vs. Chicago
42 Dontrelle Inman, San Diego at Oakland
43 Tajae Sharpe, Tennessee at Miami
44 Brice Butler, Dallas vs. Cincinnati …UPDATE: Dez Bryant did not practice all week and we are assuming he is OUT this week, leaving Butler to get the start again this week
45 John Brown, Arizona at San Francisco
46 Jamison Crowder, Washington at Baltimore
47 Brian Quick, Los Angeles vs. Buffalo …Getting on the sleeper radar, Quick has caught three touchdowns in the last two games
48 Jeremy Kerley, San Francisco vs. Arizona
49 Devin Funchess, Carolina vs. Tampa Bay …Funchess (toe) will need to be monitored; UPDATE: Funchess got in a full practice Friday and was taken off the injury report for Week 5
50 Michael Floyd, Arizona at San Francisco
51 Terrance Williams, Dallas vs. Cincinnati
52 Pierre Garcon, Washington at Baltimore
53 Tavon Austin, Los Angeles vs. Buffalo
54 Cameron Meredith, Chicago at Indianapolis …Meredith will get the start if Eddie Royal can’t play and has some deep sleeper potential regardless
55 Mohamed Sanu, Atlanta at Denver
56 Cordarrelle Patterson, Minnesota vs. Houston …UPDATE: Patterson should start with Stephon Diggs (groin) now listed as a Doubtful
57 Markus Wheaton, Pittsburgh vs. N.Y. Jets
58 Kenny Britt, Los Angeles vs. Buffalo
59 Brandon LaFell, Cincinnati at Dallas
60 Vincent Jackson, Tampa Bay at Carolina
61 Dorial Green-Beckham, Philadelphia at Detroit
62 Tyler Boyd, Cincinnati at Dallas
63 Nelson Agholor, Philadelphia at Detroit
64 Adam Humphries, Tampa Bay at Carolina
65 Ted Ginn Jr., Carolina vs. Tampa Bay
66 Andre Johnson, Tennessee at Miami
67 Charles Johnson, Minnesota vs. Houston
68 Dez Bryant, Dallas vs. Cincinnati …Bryant (hairline fracture near knee) will need to be monitored but he could return this week; UPDATE: Bryant did not practice all week and we are assuming he is OUT this week
69 Eddie Royal, Chicago at Indianapolis …UPDATE: Royal (calf) is questionabe but it is looking like he won’t play or be limited if he does
70 Rishard Matthews, Tennessee at Miami
71 Stefon Diggs, Minnesota vs. Houston …UPDATE: Diggs (groin) didn’t practice all week and is listed as Doubtful
72 Seth Roberts, Oakland vs. San Diego
73 Philly Brown, Carolina vs. Tampa Bay
74 Marquise Goodwin, Buffalo at Los Angeles
75 Breshad Perriman, Baltimore vs. Washington


Tight End
1 Jordan Reed, Washington at Baltimore
2 Greg Olsen, Carolina vs. Tampa Bay
3 Rob Gronkowski, New England at Cleveland
4 Hunter Henry, San Diego at Oakland
5 Martellus Bennett, New England at Cleveland
6 Kyle Rudolph, Minnesota vs. Houston
7 Gary Barnidge, Cleveland vs. New England
8 Jason Witten, Dallas vs. Cincinnati
9 Zach Miller, Chicago at Indianapolis
10 Dennis Pitta, Baltimore vs. Washington
11 Cameron Brate, Tampa Bay at Carolina
12 Delanie Walker, Tennessee at Miami
13 Richard Rodgers, Green Bay vs. N.Y. Giants …Jared Cook (high-ankle sprain) will be out about a month leaving Richard Rodgers to be the guy at tight end for the Packers, and Rodgers had 8 TDs last year in that role
14 Will Tye, N.Y. Giants at Green Bay …UPDATE: Tye gets a boost with Larry Donnell (concussion) ruled OUT
15 Virgil Green, Denver vs. Atlanta …Green (calf) is expected to return to action this week and in a strong match-up (Atlanta allows the 2nd-most fantasy points to opposing tight ends)
16 Zach Ertz, Philadelphia at Detroit …Ertz (ribs) will need to be monitored but he is expected to make his return to action this week, and against a defense that allows the most fantasy points to opposing tight ends
17 Charles Clay, Buffalo at Los Angeles
18 Jack Doyle, Indianapolis vs. Chicago
19 Dwayne Allen, Indianapolis vs. Chicago
20 Jesse James, Pittsburgh vs. N.Y. Jets
21 Clive Walford, Oakland vs. San Diego …UPDATE: Walford is questionable (knee) and has been limited all week
22 Lance Kendricks, Los Angeles vs. Buffalo
23 Ryan Griffin, Houston at Minnesota
24 C.J. Uzomah, Cincinnati at Dallas
25 Dion Sims, Miami vs. Tennessee
26 Garrett Celek, San Francisco vs. Arizona
27 Jacob Tamme, Atlanta at Denver
28 Trey Burton, Philadelphia at Detroit
29 Austin Hooper, Atlanta at Denver
30 Jeff Heuerman, Denver vs. Atlanta


1 Justin Tucker, Baltimore vs. Washington
2 Graham Gano, Carolina vs. Tampa Bay
3 Mason Crosby, Green Bay vs. N.Y. Giants
4 Stephen Gostkowski, New England at Cleveland
5 Blair Walsh, Minnesota vs. Houston
6 Mike Nugent, Cincinnati at Dallas
7 Chris Boswell, Pittsburgh vs. N.Y. Jets
8 Sebastian Janikowski, Oakland vs. San Diego
9 Caleb Sturgis, Philadelphia at Detroit
10 Brandon McManus, Denver vs. Atlanta
11 Adam Vinatieri, Indianapolis vs. Chicago
12 Chandler Catanzaro, Arizona at San Francisco
13 Josh Brown, N.Y. Giants at Green Bay
14 Josh Lambo, San Diego at Oakland
15 Dustin Hopkins, Washington at Baltimore
16 Dan Carpenter, Buffalo at Los Angeles
17 Matt Prater, Detroit vs. Philadelphia
18 Connor Barth, Chicago at Indianapolis
19 Ryan Succop, Tennessee at Miami
20 Matt Bryant, Atlanta at Denver
21 Andrew Franks, Miami vs. Tennessee
22 Greg Zuerlein, Los Angeles vs. Buffalo
23 Dan Bailey, Dallas vs. Cincinnati …Note: Bailey has a back injury and may not be able to go this week
24 Nick Novak, Houston at Minnesota
25 Nick Folk, N.Y. Jets at Pittsburgh
26 Phil Dawson, San Francisco vs. Arizona
27 Roberto Aguayo, Tampa Bay at Carolina
28 Cody Parkey, Cleveland vs. New England


1 Minnesota DT, Minnesota vs. Houston
2 Philadelphia DT, Philadelphia at Detroit
3 New England DT, New England at Cleveland
4 Pittsburgh DT, Pittsburgh vs. N.Y. Jets
5 Carolina DT, Carolina vs. Tampa Bay
6 Buffalo DT, Buffalo at Los Angeles
7 Arizona DT, Arizona at San Francisco
8 Los Angeles DT, Los Angeles vs. Buffalo
9 Miami DT, Miami vs. Tennessee
10 Baltimore DT, Baltimore vs. Washington
11 Denver DT, Denver vs. Atlanta
12 Green Bay DT, Green Bay vs. N.Y. Giants
13 Tennessee DT, Tennessee at Miami
14 Oakland DT, Oakland vs. San Diego
15 Cincinnati DT, Cincinnati at Dallas
16 Washington DT, Washington at Baltimore
17 Indianapolis DT, Indianapolis vs. Chicago
18 Dallas DT, Dallas vs. Cincinnati
19 New York Jets DT, N.Y. Jets at Pittsburgh
20 Detroit DT, Detroit vs. Philadelphia
21 Houston DT, Houston at Minnesota
22 Atlanta DT, Atlanta at Denver
23 Chicago DT, Chicago at Indianapolis
24 San Francisco DT, San Francisco vs. Arizona
25 Tampa Bay DT, Tampa Bay at Carolina
26 New York Giants DT, N.Y. Giants at Green Bay
27 San Diego DT, San Diego at Oakland
28 Cleveland DT, Cleveland vs. New England